Bio-Stress Score

Chronic stressT3 · 63MOD
Vitality reserve44MOD
Stress burden58MOD
Stress-age+4 yrMOD
14.6
↑ from 12.5
T2 · Moderate · Moderate 16–25
Improving

Moderate and improving. Cortisol rhythm is the leading driver (77/100), with dopaminergic tone close behind. Score is down 39.699999999999996 points since baseline (-5/30d). Pattern matches Burnout.

Panel 100%Visits 12Collected 2026-03-12

Trajectory

Score across every panel, fitted against elapsed days

Trend -5 / 30dSignificance t = -7.57Since baseline -39.699999999999996Forecast 1 ±8 · 1 mo

Direction is called from the fitted slope against its own standard error, so visit count, spacing and scatter decide what counts as a real move.

Systems

What's holding the score up

Cortisol rhythm
the main driver
major
Dopaminergic tone
moderate
Serotonergic tone
moderate
Anabolic balance
minor
Cortisol output
minor
Sympathetic drive
minor

Key findings

Ranked by the same severity that drives the score

  • 77Cortisol rhythm is the leading driver (77/100).
  • 95Blunted awakening response — CAR -22.8% (healthy 36.1–113).
  • 72Dopaminergic tone low — dopamine 97.2 µmol/mol (healthy 115–247).

Markers driving the score

Measured against the healthy population's central 95% — dashboard-side detail, not part of the HPS score

MarkerValueExpectedLoad
Cortisol awakening response
Cortisol rhythm
-22.8 %36.1 – 11395
Cortisol (evening)
Cortisol rhythmEVI1
2.95 nmol/L0.41 – 2.5974
5-HIAA
Serotonergic toneEVI2
1.08 mmol/mol1.31 – 2.8373
Dopamine
Dopaminergic toneEVI2
Low drive/motivation context.
Confounders: 12h urine; creatinine-normalised; diet.
97.2 µmol/mol114.6 – 246.772
Cortisol (night)
Cortisol rhythmEVI1
1.27 nmol/L0.26 – 1.1671
DOPAC
Dopaminergic toneEVI3
1.19 mg/g1.07 – 2.9351
5-HIAA : serotonin
Serotonergic tone
0.02 ratio0.02 – 0.0648
DHEA
Anabolic balanceEVI2
0.74 nmol/L0.62 – 1.9447

Pillars

The behavioural levers

Nutrition
skipped meals
lever
Work rhythm
lever
Movement
53%
Mindful practice
strong

Behavioural levers are reported by the care team — no biochemical panel measures them, and they do not enter the score.

Read quality

What this score rests on, and what it does not account for

Panel coverage 100%10 values derivedBurnout · p=1.00Cycle phase not modelledMedication effects not modelled

Weights and calibration are not shown here — they live in the clinical validation console. This screen shows the decomposition and drivers, not the engine internals.

Confidence

1.00High

Derived from panel completeness — 100% of scored markers present, 100% of the HPA and anabolic core.

Provenance · L0 → L7

How BIO_STRESS_SCORE became 14.6 · T2 — every layer, with what it produced

Every value above is read from this patient's own panel at render time. Sub-weights, thresholds and the phenotype posterior are withheld — they are engine internals, restricted to model governance on de-identified data.